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Vol2 Paper 14

posted Aug 18, 2018, 11:50 AM by Yaseen Raouf Mohammed   [ updated Sep 4, 2018, 1:58 AM ]
 ESTIMATION OF THE CONCENTRATION OF MAGNESIUM IN HEPATITIS B PATIENTS SERUM IN FALLUJAH DISTRICT


 Wahran M.Saod

 Department of Chemistry, Faculty of Science, University of Anbar, Ramadi, IRAQ

 Tahseen .A. Zaidan

 Department of Chemistry, Faculty of Science, University of Anbar, Ramadi, IRAQ

 Abdul Wahab .A. Alfaluji

 Fallujah teaching hospital, Fallujah, IRAQ

 ABSTRACT
The aims of this study are: to compare the level of Magnesium in sera of patients infected with HBV and healthy participants, and to evaluate the efficiency of analytical techniques (Inductively Coupled plasma- Mass spectrometry (ICP-MS), Atomic Absorption Spectroscopy that are currently used to detect Magnesium in Patients’ human sera. One hundred sixty patients’ samples and thirty healthy individuals were investigated in this study. All the patients included in this research were tested positive for HBS Ag test and their specimens were examined by profile test which include (HBS Ab, HBe Ag, HBe Ab, HBc Ab ,(IgM-IgG), HCV and HIV) and also viral load (HBV PCR) with unit (copies/ml) were carried to test the patients sera. Magnesium levels was determined by using Atomic Absorption Spectroscopy inductively oupled plasma- Mass spectrometry (ICP-MS), the measured readings of AAS and ICP-MS for Magnesium was compared. The findings of this study show that the concentration range of Magnesium element between (1.59±0.30 mg\l) to (1.74±0.17mg\l).
Serum Magnesium has shown decrease in mean serum concentration in patients with chronic hepatitis B compared to healthy individuals. Moreover, (AAS and ICP-MS) analytical techniques have same efficiency in measuring the Magnesium concentration.


 Keywords:
Hepatitis, B, Serum, Magnesium and ICP-MS.



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