Vol2 Paper 15

posted Aug 18, 2018, 12:35 PM by Yaseen Raouf Mohammed   [ updated Sep 4, 2018, 2:01 AM ]
 EXPIRED DRUG AND CORROSION: A NEW APPLICATION OF INHIBITION IN 1M H2SO4- CARBON STEEL


 Thaera Abdulridha Mussa

 Directorate of Materials Research, Ministry of Science and Technology, Baghdad, Iraq.

 Kafa Khalaf Hammud

 Directorate of Materials Research, Ministry of Science and Technology, Baghdad, Iraq.

 Samira Ahmed Abdul Rahmman

 Directorate of Materials Research, Ministry of Science and Technology, Baghdad, Iraq.

 Faliah Hassan Ali

 Directorate of Materials Research, Ministry of Science and Technology, Baghdad, Iraq.

 ABSTRACT
Different expired pharmaceutical materials were tested in 1M H2SO4- Carbon Steel and compared with 1M HCl carbon steel results that previously published. The comparison was made with Citicoline; Carbocisteine (5%); or Paracetamol.
Because weight loss is less accuracy than other methods, inhibition efficiencies ( IE% ) was from low to high values and this might be a result of active chemical component in drug, exposure time, applied concentration beside acidic hydrolysis .
In sulfuric acid, Kads were ranged from (5.5072, 407.682, and 0.4418) to (22.8355, 2217.057, and 22.6975) for Citicoline, Paracetamol, and Carbocisteine, respectively. While Δ Gadsvalues (in negative sign) were varied from (14.1777, 22.5925, and 7.92718) to (17.7015, 29.0379, and 17.6865) for Citicoline, Paracetamol, and Carbocisteine respectively in the same corrosive solution. From Δ Gads values, it can be concluded that physisorpion than chemisorption might be occurred in 1M H2SO4 medium.


Keywords:
carbon steel, expired drugs, corrosion, weight loss, paracetamol, citicoline, carbocisteine.



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